Vol. 4 No. 1 (2025): The QUEST: Journal of Multidisciplinary Research and Development
Articles

Optimization of Different Extraction Methods in Determining the Bioactive Potential of Crown-of-Thorn Starfish (COTS)

  • Chia Ren Punzal,
  • Krystel Grace Padilla,
  • Danny Alfonso,
  • Rachelle Conmigo
Chia Ren Punzal
Nueva Ecija University of Science and Technology
Krystel Grace Padilla
Nueva Ecija University of Science and Technology
Danny Alfonso
Nueva Ecija University of Science and Technology
Rachelle Conmigo
Nueva Ecija University of Science and Technology
DOI: https://doi.org/10.60008/thequest.v4i1.251

Published 06/30/2025

Keywords

  • air-dried; bioactive compounds; COTS; freeze-dried; gonads

How to Cite

Punzal, C. R., Padilla, K. G., Alfonso, D., & Conmigo, R. (2025). Optimization of Different Extraction Methods in Determining the Bioactive Potential of Crown-of-Thorn Starfish (COTS). The QUEST: Journal of Multidisciplinary Research and Development, 4(1). https://doi.org/10.60008/thequest.v4i1.251

Copyright (c) 2025 The QUEST: Journal of Multidisciplinary Research and Development

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Abstract

The COTS is a giant corallivorous predatory starfish that consumes large areas of coral, causing damage to the marine ecosystem, and has potential applications for medicinal and pharmaceutical purposes. This study sought to investigate the effect of different extraction methods in determining the bioactive potential of A. planci. Ethanol solvents were used to obtain the crude extracts of AD, FD, and GD samples of A. planci. The phytochemical screening revealed that the FD extract of A. planci had the presence of flavonoids, phenolics and tannins, glycosides, coumarin, terpenoids, reducing sugars, amino acids, and proteins. While AD and GD extracts were positive in the presence of flavonoids, phenolics and tannins, saponins, glycosides, coumarin, terpenoids, reducing sugars, amino acids, and proteins. All extracts showed no antibacterial potential against S. aureus ATCC 6538, P. aeruginosa ATCC 27853, E. coli ATCC  25922, and S. aureus ATCC 1582. But, zoochemical analysis shows a promising innovative source of unique bioactive compounds for developing marine-derived drugs and other purposes.

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